SCIENCE

Involved in many disease pathologies, DUBs are attractive therapeutic targets

PLATFORM

World-leading DUB platform translating scientific advances into transformative therapies

PIPELINE

First-in-class small molecule DUB inhibitors developed in-house and with partners

USP30

Multiple in-house DUB inhibitor programs in the clinic or approaching clinical development

Mission Therapeutics

Mission Therapeutics is determined to make a positive impact on the lives of patients suffering from serious diseases including Parkinson’s Disease (PD) and other neuro-degenerative conditions, heart and kidney diseases, fibrosis, and rare mitochondria diseases, by developing first-in-class therapeutics that inhibit disease-associated deubiquitylating enzymes (DUBs).

Our lead candidates – MTX325 and MTX652 – aim to inhibit USP30, a DUB which can retard the essential cellular quality control process called mitophagy.

To hear our CEO discuss our technology, programs, recent progress and strategy, watch our Corporate Presentation.

2011

Founded

£117 million

Capital Investment

55

DUB targets explored

#1

In the DUB field

Commercializing expert research into

Dubs and Ubiquitin pathway

Mission Therapeutics’ strategy is to create value by advancing its pipeline programs through early clinical development, and preferentially with a patient selection strategy to enhance the probability of demonstrating early signs of efficacy. Selected programmes may be advanced in partnership with other pharmaceutical companies.

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